5-Amino-1MQ 10mg

Description

5-Amino-1MQ, also known as 5-amino-1-methylquinolinium, is a small-molecule research compound studied as a selective inhibitor of nicotinamide N-methyltransferase, commonly known as NNMT. This enzyme is widely researched for its involvement in cellular metabolism, energy regulation, and related biochemical pathways.

In laboratory studies, 5-Amino-1MQ has been used to examine how NNMT activity may influence NAD+ salvage mechanisms, methionine metabolism, and cellular differentiation pathways. Published in vitro research has reported measurable changes in genes associated with lipid production when NNMT is inhibited in cultured adipocyte cells, making this compound a valuable tool in metabolic biochemistry research.

Researchers also use 5-Amino-1MQ to investigate skeletal muscle metabolism, cellular energy production, and epigenetic methylation processes. Its selectivity for NNMT compared with other methyltransferase enzymes makes it especially useful for pathway-specific studies where reducing unintended activity is important.

Current research interest focuses on how NNMT inhibition may influence the relationship between one-carbon metabolism, NAD+ availability, and cellular energy signaling. These mechanisms are studied across several mammalian cell types, including adipocytes, hepatocytes, and myocytes.

Each vial from PEPTEX Labs contains research-grade 5-Amino-1MQ produced under controlled quality standards. Products are accompanied by a certificate of analysis confirming identity, molecular weight, and purity as stated on the applicable certificate of analysis.

This product is supplied exclusively for qualified laboratory research and is not intended for human or veterinary use.